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Clofranil (Clomipramine)

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Clofranil is a tricyclic antidepressant used in the treatment of obsessive-compulsive disorder and disorders with an obsessive-compulsive component, such as depression, schizophrenia, and Tourette’s disorder.

Other names for this medication:
Clofranil, Clomi, Clomifril, Clomijet, Clomilent, Clomine, Clominex, Clomip, Clomipramine, Clomistar, Clonil, Clopic, Ecmin, Lodep, Obsenil, Ocifiril, Ocifril, Ocnil, Syconil, Ultradep

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Also known as: Clomipramine


Generic Clofranil is used to treat symptoms of obsessive-compulsive disorder (recurrent thoughts or feelings and repetitive actions). Generic Clofranil is a tricyclic antidepressant. Clofranil is also known as Clomipramine, Clonil, Clofranil, Clopram, Clopran, Clopress, Equinorm, Hydiphen. Generic Clofranil works by affecting chemicals in the brain that may become unbalanced. Generic name of Generic Clofranil is Clomipramine. Brand name of Generic Clofranil is Clofranil.


Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

It may take up to 4 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 4 weeks of treatment.

Call your doctor if your symptoms do not improve, or if they get worse.

If you need surgery, tell your surgeon you currently use Clofranil. You may need to stop for a short time.

Do not stop using Clofranil suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

Detailed Clofranil dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Clofranil can be fatal.

Overdose symptoms may include irregular heartbeats, feeling restless or agitated, confusion, severe sweating, slow or jerky muscle movements, extreme drowsiness, slow breathing, feeling like you might pass out, seizure, or coma.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Clofranil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Avoid drinking alcohol. Dangerous side effects could occur.

Avoid driving or hazardous activity until you know how Clofranil will affect you. Your reactions could be impaired.

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During the attacks of trigeminal neuralgia, beta-endorphin levels of plasma from external jugular, cubital fossa vein blood ipsilateral to the pain and contralateral external jugular vein blood were assessed by sensitive radioimmunoassay in 12 cases, after operations the venous blood from the ipsilateral external jugular vein was sampled again, the external jugular vein blood of 12 normal volunteers was collected as control. Early benefit assessment (EBA) in Germany: analysing decisions 18 months after introducing the new AMNOG legislation. As possible contributory factors palatal morphometric parameters, as well as tongue pressure were also measured. The analogy between the wave-vortex interaction and the Aharonov-Bohm effect in quantum mechanics is explored by contrasting the Burgers vectors of dislocations as well as the form of the scattered wave in both cases. Quality assurance programs based on immediate outcome indicators can be effective if embedded in Continuous Quality Improvement. To determine the rate of device-associated healthcare-associated infection (DA-HAI), microbiological profile, length of stay (LOS), extra mortality, and hand hygiene compliance in two intensive care units (ICUs) of two hospital members of the International Infection Control Consortium (INICC) of Havana, Cuba. Stimulation of ethylene production in apple tissue slices by methionine. Life table analyses were undertaken to examine the difference in CSR between the groups.

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Fatigued nurses also endanger others during their commute to and from work. Lipopolysaccharide (LPS) prepared from both the clinical isolates produced three major precipitin lines when reacted with their homologous antisera in crossed immunoelectrophoresis (CIE). Isolation and identification of neuroblast precursor cells from mouse neopallium. These studies also indicate that difference in structure do not affect the binding sites and inhibition of amine uptake. The levels of Lunx mRNA in the pleural effusions were determined by real-time PCR. Taken together, these data demonstrated oxidant-dependent activation of NF-kappaB and enhanced MMP expression by alveolar macrophages from SP-D-/- mice, a process likely to mediate airspace remodeling caused by SP-D deficiency. The risk percived by the patients is very less and attitude toward the illness is bengine as there is no clear understanding about the causation.

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Surface hydrocarbons of queen eggs regulate worker reproduction in a social insect. A greater focus on education, accreditation and database implementation is needed to promote CR availability and the quality of CR services for the benefit of cardiac patients across Europe. Although it reflects clinical judgement, it has been criticised for its lack of transparency. An improved version of the MobileMums program is being compared with a minimal contact control group in a large randomised controlled trial (RCT). In nine other cases, radiographs showed an absence of hemo- or pneumothorax. The production by the cap cells of basipetally transported growth inhibitors was tested (biologically by the curvature of half-decapped roots) and found to be significantly higher for longer root caps than that for shorter ones. ASW was identified as a tandemly repeated gene conserved on avian W chromosomes that is expressed in early female development and appears to be an inactive form of avian Z-encoded HINT.

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A combination of several equilibrium chromatographic steps permitted us to purify thirteen proteins from the venom of Buthus occitanus tunetanus using the mouse as the test animal for lethality measurement. The relationship between this time interval and the final visual outcome was analyzed. Rat jejunum was perfused in vivo with sodium deoxycholate concentrations ranging from 0.125 to 4 mM. Anatomical study about the posterior coaxial portals via posterior tibial tendon sheath for ankle arthroscopy. Role of sodium in the control of compartmental distribution of water during hemodialysis. Changing patterns of migration to Australia and their influence on the health of migrants. To examine roles of Fgf22 in midbrain development, we analyzed fgf22 knockdown embryos. Perceived barriers to health service access affect decisions to consult, but some patients develop strategies to get round them.

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Other markers have been proposed including serum cystatin C (cysC) and the Modification of Diet in Renal Disease (MDRD) study equation. During a 5-year period, 54 patients underwent emergency percutaneous transhepatic protography for embolization of varices to control gastrointestinal bleeding. Ambulatory 24-hour double-probe pH monitoring seems to be the best test to measure reflux. The in vivo microscopic technique presented enables lymph vessels and cell trafficking to be studied in high resolution in a minimally-perturbed physiologic milieu. Helicobacter pylori and antimicrobial susceptibility in children. Thallium-201 rest myocardial perfusion scintiscans performed in two of the four patients demonstrated a defect corresponding to the neck of the false aneurysm in one patient and a larger defect in the second patient with both a true and false aneurysm. Underreporting of infectious diseases remains a major problem in communicable diseases surveillance. Elicitation of drug resistance and various survival strategies inside host macrophages have been the hallmarks of Mycobacterium tuberculosis as a successful pathogen. Five trials were conducted to evaluate the virulence and the vaccination efficacy of the F, R, S6, and A5969 strains of Mycoplasma gallisepticum (MG) at different in vitro passage levels.

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The 15 target drugs were previously identified based on frequency of use in our health care system and risk of serious adverse events. Different residues in the GABAA receptor benzodiazepine binding pocket mediate benzodiazepine efficacy and binding. Since these effects are characteristic in patients with systemic sclerosis (SSc), serum concentrations of sCD40L were determined in patients with SSc. These data indicate that there is a species difference in the autoreceptor control of 5-HT release. Quantification of healthy and atretic germ cells and follicles in the developing and post-natal ovary of the South American plains vizcacha, Lagostomus maximus: evidence of continuous rise of the germinal reserve.

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Separable routes to human memory formation: dissociating task and material contributions in the prefrontal cortex. Cholesterol-dependent partitioning of PtdIns(4,5)P2 into membrane domains by the N-terminal fragment of NAP-22 (neuronal axonal myristoylated membrane protein of 22 kDa). Incidence of protein deficiency in relation to different diets in India. Here a possible role for amphiphilic molecules inducing symmetry breaking is suggested in the framework of the research on origin of life. Three major types of study design have been used to investigate such a relation: clinic-based case-control studies, retrospective case-control studies, and nested case-control studies. Browning-associated mechanisms of resistance to insects in corn callus tissue. It is possible that coasting alters the capacity of vasotec dosing the granulosa cells to produce VEGF and/or their response to hCG and in this way acts to reduce the severity and incidence of severe OHSS. Even more uncommon is such involvement of excluded and defunctionalized small bowel segments.

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Special note is made of the high rate of fibrous capsule contraction. Our results also have implications for the evolution of complex birdsongs and song control nuclei in oscine birds. In farmed Atlantic salmon, cardiomyopathy syndrome (CMS) is a common viral disease associated with severe cardiac inflammation that may be accompanied by heavy melanisation of the heart. Frequently, field teaching is characterized by conflictual situations involving students, field instructors and university faculty. In behavioral studies, stimulant-pretreated rats showed behavioral sensitization characterized by enhanced behavioral response to the rewarding or reinforcing effects of psychostimulants. Temporal subtraction improved the diagnostic accuracy of radiologists in detecting interval changes in interstitial lung diseases on chest radiographs. The patient had a family history of similar aneurysms and also of a rare spingolipidosis, Anderson-Fabry disease. We speculate that pacemaker activity arising from the prostatic interstitial cells (PICs) is likely to propagate and initiate slow wave activity in the smooth muscle cells resulting in contraction of the stromal smooth muscle wall. The free fatty acid receptor GPR40 generates excitement in pancreatic beta-cells.

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This induction was independent of CodY, the major regulator of proteolytic functions in L. The effect of Taraxacum officinale on gastric emptying and smooth muscle motility in Rodents. Here, we report the isolation of CENP-A chromatin from HeLa interphase nuclei by chromatin immunoprecipitation using anti-CENP-A monoclonal antibody, and systematic identification of its components by mass spectrometric analyses. The results represent the first examples of successful isopeptide ligations starting from O-acyl Tyr-peptides. Compared with appropriate for gestational age fetus, IUGR fetus is at increased risk of metabolic acidosis or perinatal asphyxia during delivery. Improved patient survival combined with a relative static improvement in long-term graft outcomes has led to an increasing number of transplant recipients with failed allografts who face the eventual option of either returning to dialysis or seeking retransplantation.

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Pigmented poroma with unusual location and dermatoscopic features. Cross-sectional surveys of communities in Accra and Kumasi, Ghana, determining risk factors for malaria infection and anaemia in children aged 6-60 months. Most evidence on the use of pharmaceutical alternatives to morphine is anecdotal, demonstrating a need for more research to be conducted in this field. We consider its application to recent observations of slow waves in coronal loops. The major component of the sex pheromone of femaleSpodoptera littoralis, (Z,E)-9,11-tetradecadienyl acetate (1), elicited all steps of the male behavioral sequence, i.e., wing fanning and taking flight, oriented upwind flight and arrival to the middle of the tunnel, close approach and contact with the source. Videomicroscopy has successfully been used to determine CVM capillary pattern and diameter of vessels. Kaplan-Meier survival curves were generated to show the cause-specific survival.

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Pore-forming pyocin S5 utilizes the FptA ferripyochelin receptor to kill Pseudomonas aeruginosa. Changes with normal moduretic tablets aging were significant in the left and right hemispheres with bilateral changes in temporal, parietal, and occipital regions. In the present study, polypropylene (00000) suture was given a coiling property. Furthermore, the expression of genes for heme uptake changed in response to B-cell activation and heme administration. We report the case of a middle-aged male with symptomatic but clinically stable ventricular tachycardia.

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These findings indicate that infectious agents may play a role in the etiopathogenesis of some cases of schizophrenia. Effectiveness of palonosetron for preventing delayed chemotherapy-induced nausea and vomiting following moderately emetogenic chemotherapy in patients with gastrointestinal cancer. Clinically, DM2 resembles adult-onset DM1, with myotonia, muscular dystrophy, cataracts, diabetes, ventolin inhaler cost us testicular failure, hypogammaglobulinemia, and cardiac conduction defects. Magnetic resonance imaging demonstrated a tumor with mixed signal intensity in the left anterior temporal subdural area, but no evidence of rupture. This article focuses on the 2 most common acquired anemias including iron deficiency and anemia of inflammation as well as disseminated intravascular coagulation. 1H HR-MAS NMR of carotenoids in aqueous samples and raw vegetables. In fact delivering one single suprathreshold magnetic stimulus easily awakes subjects, or lightens their sleep. This is a feasible minimally invasive procedure for this condition that requires advanced reconstructive and intracorporeal suturing skills.

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Additional work should test further relations to growth, maturation and development, focusing on any adverse effect from exposure to a television screen also on obesity from a neuro-hormonal viewpoint, quite apart from any decreased activity and/or other lifestyle alterations associated with watching TV. Using fluorescence and confocal microscopy, we have confirmed that E2 is located in the ER, where budding of HCV virions is thought to occur. Resolving the complex conjugate ambiguity in Fourier-domain OCT by harmonic lock-in detection of the spectral interferogram. Examining the combined effect of biological and societal factors on disability would potentially identify existing differences between men and women with rotator cuff pathology which would help to provide suggestions for better models of care. Human HCC cells Hep3B with overexpression of MT1-MMP were established by stable transfection, and compared with control cells carrying the empty vector. In the presence of Cdc23p, Dfp1-Hsk1 phosphorylated the Mcm2p and Mcm4p subunits of the Mcm complex. The novel dental implant abutment with a micro-motion mechanism actually imitated the biomechanical behavior of a natural tooth and provided resilient function, sealing, a non-separation mechanism, and ease-of-use. Control rats were bilaterally inoculated with heat-inactivated lentiviruses. We conclude that LRP4 is a new CMS disease gene and that the 3rd beta propeller domain of LRP4 mediates the two signaling pathways in a position-specific manner.

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