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Dulex (Duloxetine)
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Dulex

Dulex is a type of antidepressant known as a serotonin–norepinephrine reuptake inhibitor used to treat depression and anxiety. Dulex may improve your mood, sleep, appetite, and energy level, and decrease nervousness.

Other names for this medication:
Ariclaim, Combac, Delok, Deneurone, Detine, Dimorex, Dulane, Dulex, Dulife, Dulojoy, Dulok, Dulonix, Dulot, Dulotin, Duloxee, Duloxetine, Duloxit, Duloxyl, Dulti, Dumore, Dutin, Duxet, Duzela, Nudep, Sylonex, Symbal, Ulozet, Verlox, Xeristar, Yentreve

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Also known as: Duloxetine

Description

Generic Dulex is developed by medical scientists to treat major depressive disorder and general anxiety disorder. It is an antidepressant in a group of drugs called selective serotonin and norepinephrine reuptake inhibitors. Generic Dulex affects chemicals in the brain that may become unbalanced and cause depression. Generic Dulex is also used to treat a chronic pain disorder called fibromyalgia, treat pain caused by nerve damage in people with diabetes (diabetic neuropathy) and to treat chronic musculoskeletal pain, including discomfort from osteoarthritis and chronic lower back pain.

Dosage

Usual Adult Dose for Depression:

Initial dose: 20 mg to 30 mg orally 2 times a day Maintenance dose: 60 mg per day, given either once a day OR 30 mg orally 2 times a day Maximum dose: 120 mg/day.

Usual Adult Dose for Fibromyalgia:

Initial dose: 30 mg orally once a day for at least 1 week Maintenance dose: 30 to 60 mg orally once a day.

Usual Adult Dose for Generalized Anxiety Disorder:

Initial dose: 60 mg orally once a day Maintenance dose: 60 to 120 mg orally once a day Maximum dose: 120 mg/day.

Usual Adult Dose for Pain:

Initial dose: 30 to 60 mg orally once a day Maintenance dose: 60 mg orally once a day.

Usual Adult Dose for Neuropathic Pain:

Initial dose: 30 to 60 mg orally once a day Maintenance dose: 60 mg orally once a day.

Usual Adult Dose for Chronic Pain:

Initial dose: 30 to 60 mg orally once a day Maintenance dose: 60 mg orally once a day.

Usual Geriatric Dose for Generalized Anxiety Disorder:

Initial dose: 30 mg orally once a day for at least 2 weeks Maintenance dose: 60 mg orally once a day Maximum dose: 120 mg/day.

Usual Pediatric Dose for Generalized Anxiety Disorder:

7 to 17 years: -Initial dose: 30 mg orally once a day for at least 2 weeks -Maintenance dose: 30 to 60 mg orally once a day -Maximum dose: 120 mg/day.

Usual Pediatric Dose for Fibromyalgia:

13 years and older: -Initial dose: 30 mg orally once a day for at least 1 week -Maintenance dose: 30 to 60 mg orally once a day.

Detailed Dulex dosage information

Overdose

If you overdose Generic Dulex and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Dulex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Dulex if you are allergic to Duloxetine, other SNRIs or to any of the medication's components. Do not take Dulex if you have taken recreational drugs such as ecstasy (MDMA), ketamine, LSD, poppers (amyl nitrate), narcotics or benzodiazepines. Do not take Dulex if you are taking other medications, including erythromycin, alpha-blockers, antifungal medications (ketoconazole and itraconazole), medications for HIV (ritonavir, saquinavir, nelfinavir and atazanavir), certain antibiotics (telithromycin), alprazolam (Xanax), anticoagulants (warfarin), antidepressants (Elavil, Asendin, Anafranil, Norpramin), MAOI antidepressants (Marplan, Nardil, Eldepryl, Emsam, Zelapar), SSRI antidepressants (fluvoxamine), herbal remedy St. John’s Wort, NSAIDs (Advil, Motrin, Aleve, Naprosyn), clopidogrel (Plavix), diazepam (Valium), digoxin (Lanoxin), diuretics ('water pills'), linezolid, flecainide (Tambocor), medications for diabetes, lithium (Eskalith, Lithobid), medications for anxiety and Parkinson's disease, methylene blue, medications for mental illness (Clozaril, Haldol), medications for migraine (Axert, Relpax, Frova, Amerge), medications for seizures (Tegretol, Dilantin), sedatives, sibutramine (Meridia), sleeping pills, tramadol (Ultram), tranquilizers, and vinblastine (Velban). Do not take Dulex if you experience seizures (convulsions or fits). Do not take Dulex if you suffer from or have history of cardiovascular disease, liver or kidney disorders, hypotension, leukemia, peptic ulcer disease, rhinitis, glaucoma, epilepsy. Do not take Dulex if you have a history of fainting, mania (feeling overexcited, irritable or not being able to think clearly) or severe depression. Do not take Dulex if you have recently undergone a surgery. Do not to consume alcohol, drive or operate machinery while using Dulex, as it can lower your blood pressure, causing dizziness, drowsiness. Dulex is not for use in patients under age 18 years.

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Expression of the specific type IV phosphodiesterase gene PDE4B3 during different phases of long-term potentiation in single hippocampal slices of rats in vitro. Such washing is laborious, lengthens assay time, and increases assay scatter. Intraoral mucosa lesion in secondary syphilis: report of 4 cases. We found that external ATP is required for maintenance of the import competence of mitochondrial precursor proteins but that, once they bind to mitochondria, the subsequent translocation of presequence-containing proteins, but not the ADP/ATP carrier, proceeds independently of external ATP. A multivariate analysis of correlates of life satisfaction in adulthood.

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A promising technique for treating circulatory arrest associated coagulopathy. The desirability function was used to select optimum separation conditions. Many patients with heart failure have stiff hearts with an increased wall thickness and small volumes leading to diastolic dysfunction. Normal brain tissues surrounding the lesions in gliomas were obtained from 49 patients among the 173 ones, with the microdissection using a laser microdissection microscope Genomic DNA was extracted from the peripheral blood cells and the normal brain tissues from the subjects. Information about prevention and survivorship arrives from a mix of sources. Cyclooxygenase-2 inhibition: vascular inflammation and cardiovascular risk.

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Our recent findings demonstrated that NgBR binds farnesylated Ras and recruits Ras to the plasma membrane, which is a critical step required for the activation of Ras signaling in human breast cancer cells and tumorigenesis. Together, our data suggest that AMACO represents a member of the Fraser complex. This new class of antimicrobials was designed to overcome current resistance mechanisms against erythromycin A within Gram-positive cocci. These data do not support the hypothesis that the less favorable review outcomes for clinical applications are related to these review factors. Evaluation of the inhibitory potential of five squaric acid derivatives against pancreatic lipase. Automobile airbags have been universally installed to save lives in motor vehicle accidents, but have also been linked with facial and thoracic burns and chest trauma during rapid deployment.

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The importance of NoVs as a major gastrointestinal pathogen underscores the need for well tolerated and effective vaccines. No differences were found between the PMNC frequencies of the negative control and the 30 and 50 mg/kg MTZ groups. Hitherto, ECC studies with grass pollen are conducted primarily outside of the pollen season to avoid the influence of natural pollen exposure. There remains a risk of late reintervention following either form of repair. Finally, surgical or genetic elimination of retinal input greatly accelerated the rate of corticogeniculate innervation, with axons invading between P2 and P3 and fully innervating dLGN by P8 to P10. A statistical survey of Canadian forensic mental health inpatient programs.

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To determine if the skills to successfully ventilate using the laryngeal mask (The Laryngeal Mask Company Limited, Henley on Thames, United Kingdom) and Combitube (The Kendall Company, Mansfield, USA) can be retained after seven months. Review of these three cases and 13 cases previously reported suggests that retained appendiceal barium may be significant when it exists in either of two patterns. We report the case of a 60-year-old man who presented with a two day history of headache, altered sensorium and left hemiplegia. Community structure of zoohydrobionts in the lake affected by chemical weapon destruction was studied for the first time. When these antibodies were saturated with cell-wall-derived glycopeptides in order to abolish the binding to carbohydrate side chains, they still recognized the same cell-wall polypeptides as did the untreated antibodies. Autoradiographic quantification of the local cerebral blood flow, calculated according to the microsphere model, produced identical results for both molecules. The human PTH receptor type 2 (PTH2R) is activated by PTH what happens if i miss a dose of wellbutrin xl and tuberoinfundibular peptide of 39 residues (TIP39), resulting in cAMP and intracellular Ca signaling. After pre-operative administration of 1 g, latamoxef disodium (moxalactam) levels were measured in peripheral venous blood, skeletal muscle and subcutaneous fat sampled from 29 patients during either arterial reconstruction or amputation undertaken for arterial occlusive disease. We studied the acute toxicity of MCA before clinical symptoms appeared in fasting rats. Seven-tesla magnetic resonance imaging in Wilson disease using quantitative susceptibility mapping for measurement of copper accumulation.

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