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Fisat

Fisat is a combination of two synthetic (man-made) antibiotics, sulfamethoxazole and trimethoprim. Both drugs reduce the ability of some bacteria to utilize folic acid for growing. Sulfamethoxazole is an anti-bacterial sulfonamide, a sulfa drug.

Other names for this medication:
Bactoprim, Biotrim, Biseptrin, Cadiprim, Ciplin, Cosat, Cotrimol, Drylin, Esbesul, Globaxol, Ifitrim, Methoxasol, Metoxiprim, Nopil, Primotren, Sinersul, Soltrim, Suftrex, Sulfatrim, Sulfoid, Sulphatrim, Sumetrolim, Sutrim, Trelibec, Triforam, Trizole, Urobactrim, Wiatrim

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Also known as: Trimethoprim

Description

Fisat is effective in a variety of upper and lower respiratory tract infections, renal and urinary tract infections, gastrointestinal tract infections, skin and wound infections, septicaemias and other infections caused by sensitive organisms.

Each Fisat tablet contains 80 mg trimethoprim and 400 mg sulfamethoxazole.

Each Fisat DS (double strength) tablet contains 160 mg trimethoprim and 800 mg sulfamethoxazole.

Dosage

This section provides information on the proper use of a number of products that contain sulfamethoxazole and trimethoprim. It may not be specific to Fisat DS. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

Sulfamethoxazole and trimethoprim combination is best taken with a full glass (8 ounces) of water. Several additional glasses of water should be taken every day, unless otherwise directed by your doctor. Drinking extra water will help to prevent some unwanted effects (eg, crystals in the urine). .

For patients taking the oral liquid, use a specially marked measuring spoon or other device to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.

To help clear up your infection completely, keep using this medicine for the full time of treatment, even if you begin to feel better after a few days. If you stop taking this medicine too soon, your symptoms may return.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (liquid or tablets): For treatment of bacterial infections: Adults—1 tablet (DS tablet) of 800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim, 2 tablets of 400 mg of sulfamethoxazole and 80 mg of trimethoprim, or 4 teaspoonfuls or 20 milliliters (mL) of oral liquid every 12 hours for 10 to 14 days. Your doctor may adjust this dose if needed. Children 2 months of age and older—Dose is based on body weight and must be determined by your doctor. The usual dose is 40 milligrams (mg) per kilogram of body weight of sulfamethoxazole and 8 milligrams (mg) per kilogram of body weight of trimethoprim, given in two divided doses every 12 hours for 10 days. Weighing 40 kilograms (kg)—4 teaspoonfuls (20 mL) of oral liquid or 2 tablets (or 1 DS tablet) 2 times a day for 10 days. Weighing 30 kg—3 teaspoonfuls (15 mL) of oral liquid or 1 ½ tablet 2 times a day for 10 days. Weighing 20 kg—2 teaspoonfuls (10 mL) of oral liquid or 1 tablet 2 times a day for 10 days. Weighing 10 kg—1 teaspoonful (5 mL) of oral liquid 2 times a day for 10 days. Children younger than 2 months of age—Use is not recommended. For treatment of bronchitis: Adults—1 tablet (DS tablet) of 800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim, 2 tablets of 400 mg of sulfamethoxazole and 80 mg of trimethoprim, or 4 teaspoonfuls or 20 milliliters (mL) of oral liquid every 12 hours for 14 days. Children 2 months of age and older—Use and dose must be determined by your doctor. Children younger than 2 months of age—Use is not recommended. For treatment of Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP): Adults and children 2 months of age and older—Dose is based on body weight and must be determined by your doctor. The usual dose is 75 to 100 milligrams (mg) per kilogram of body weight of sulfamethoxazole and 15 to 20 milligrams (mg) per kilogram of body weight of trimethoprim each day, given in equally divided doses every 6 hours for 14 to 21 days. Weighing 80 kilograms (kg)—10 teaspoonfuls (50 milliliters (mL)) or 5 tablets (or 2 ½ DS tablets) 4 times a day for 14 to 21 days. Weighing 64 kg—8 teaspoonfuls (40 mL) or 4 tablets (or 2 DS tablets) 4 times a day for 14 to 21 days. Weighing 48 kg—6 teaspoonfuls (30 mL) or 3 tablets (or 1 ½ DS tablets) 4 times a day for 14 to 21 days. Weighing 40 kg—5 teaspoonfuls (25 mL) or 2 ½ tablets 4 times a day for 14 to 21 days. Weighing 32 kg—4 teaspoonfuls (20 mL) or 2 tablets (or 1 DS tablet) 4 times a day for 14 to 21 days. Weighing 24 kg—3 teaspoonfuls (15 mL) or 1 ½ tablets 4 times a day for 14 to 21 days. Weighing 16 kg—2 teaspoonfuls (10 mL) or 1 tablet 4 times a day for 14 to 21 days. Weighing 8 kg—1 teaspoonful (5 mL) 4 times a day for 14 to 21 days. Children younger than 2 months of age—Use is not recommended. For prevention of Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP): Adults—800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim once a day. Children 2 months of age and older—Dose is based on body size and must be determined by your doctor. The usual dose is 750 mg of sulfamethoxazole and 150 mg of trimethoprim per square meter (m[2]) of body surface each day. This is given in equally divided doses two times a day for 3 days a week on consecutive days (eg, Monday, Tuesday, Wednesday). However, the dose is usually not more than 1600 mg of sulfamethoxazole and 320 mg of trimethoprim per day. Children younger than 2 months of age—Use is not recommended. For treatment of traveler's diarrhea: Adults—1 tablet (DS tablet) of 800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim, 2 tablets of 400 mg of sulfamethoxazole and 80 mg of trimethoprim, or 4 teaspoonfuls or 20 milliliters (mL) of oral liquid every 12 hours for 5 days. Children 2 months of age and older—Use and dose must be determined by your doctor. Children younger than 2 months of age—Use is not recommended.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include loss of appetite, vomiting, fever, blood in your urine, yellowing of your skin or eyes, confusion, or loss of consciousness.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Side effects

The most common side effects associated with Fisat are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Fisat is contraindicated in pediatric patients less than 2 months of age.

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From January 2001 to September 2004, 8 men 34 to 65 years old (mean age 46.1) with urethral strictures 1.5 to 4.5 cm long were selected for 1-stage dorsal onlay urethroplasty. Appropriate selection and understanding of the pharmaceuticals used in these procedures is necessary to minimize complications and maximize successful outcomes. We evaluated the efficacy and safety of TSU-68 in combination with transarterial chemoembolisation (TACE) in patients with intermediate-stage hepatocellular carcinoma (HCC). Sacral nerve stimulation is becoming the standard of care for refractory overactive bladder and retention problems. The results indicate that this system is achievable to produce these domain peptides with high solubility and stability for further biochemical characterization. Twelve hours later the venous pressures were the lowest recorded during the study. To evaluate a new approach for recanalization (RC) of nasolacrimal duct obstruction in the treatment of the symptomatic nasolacrimal duct obstruction (NLDO).

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Cases of work incapacitation due to trauma according to days of the week and to various months of the year (according to the data of Saratov polyclinic No. The conclusions of this paper suggest that lower infant mortality rates can be reached by implementing a set of coherent public policy actions including an increase and reorganization of hospital infrastructure, quality improvement, and increasing demand for health by poor families. Compound delivered by inhalation may be effective in the lung but rapidly cleared otherwise, limiting systemic exposure. We generated Nmnat1-overexpressing transgenic mice whose Nmnat activities closely match that of Wld(S) mice. Gastrointestinal transport was similar and comparably affected by guanfacine in all rat strains. Maternal KSP somatic anxiety (OR 1.74, CI 1.04-2.91) and psychic anxiety (OR 1.74, CI 1.05-2.86) was significantly associated with breathlessness reported by the adolescent child. In this study, we generated immortalized human amniotic epithelial (IHAE) cells to maintain the effect of implantation, and encapsulated these cells to prevent harmful immunological response and tumor formation and to regulate the level of GUSB expression within the host.

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military fatalities due to Neisseria meningitidis: case reports and historical perspective. Mean serum SOD activity was found to be elevated in patients with BD compared to controls. The irregularities in motility due to irradiation are probably related to the damaged centrioles. As distant metastasis was not found and as cytological examination of pleural effusion gave a result of class II, we attempted to perform left pneumonectomy. The comparison of hand preferences revealed a greater right-sided asymmetry for declarative pointing than for non-communicative activities, whereas there was no difference between imperative pointing and non-communicative activities, or between symbolic gestures and non-communicative activities. The use of novel approaches, such as whole-exome sequencing and mouse genetic engineering, has helped to identify new genes that are involved in the pathogenesis of PADs and has enabled the characterization of the molecular pathways that are involved in B cell development and function. Single and combination toxic metal exposures induce apoptosis in cultured murine podocytes exclusively via the extrinsic caspase 8 pathway. Pancreatic acinar-like metaplasia has previously been described in the gastric mucosa and in the distal part of the oesophagus.

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The CCN proteins contain an N-terminal signal peptide followed by four conserved domains sharing sequence similarities with the insulin-like growth factor binding proteins, von Willebrand factor type C repeat, thrombospondin type 1 repeat, and a C-terminal growth factor cysteine knot domain. Travelers from all regions except Southeast Asia presented with parasite-induced diarrhea more often than with bacterial diarrhea. This heterogeneity can include copy number variations (CNVs), inversions, insertions, deletions and other complex rearrangements, most of which are not detected by standard cytogenetics or DNA sequencing. The mechanism behind accumulation of cholestanol in brain and tendons of patients with CTX has been clarified but it is not known why this accumulation is associated with parallel accumulation of cholesterol and formation of xanthomas. Integration of stress signals by homeodomain interacting protein kinases. Older adults experience an increase in distress that is not due solely to declines in physical health or approaching death. Synthesis, characterization and electrocatalytic activity of fused gold nanoparticles. We found that TGFbeta1 and FGF-2 stimulated ECM synthesis of fibroblasts. We studied the possible role of the choroidal circulation in stabilizing the temperature environment of the retina and the retinal pigment epithelium.

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In the last two decades it was shown that plants have a great potential for production of specific heterologous proteins. In addition to the classical brown adipocytes, thermogenic brown-like adipocytes (brite/beige cells) may appear within white adipose tissue (WAT) depots, sharing many of the morphological and functional features of brown adipocytes, but arising from a Myf5-negative lineage. In the field study, the difference in efficiency between the two types of collector was fairly small. Management of pediatric intracranial arteriovenous malformations: experience with multimodality therapy. The high purity and viability of cells attained by this method, makes them suitable for functional analysis in vitro. These blond strains had significantly smaller body weights than corresponding ones with the same color pattern but with the wild-type grey-brown background coloration due to the dominant allele (BB). There was no Myo detected in the cases of metastasis and abscess. Thus, the SNAIL signaling pathway may provide a novel therapeutic target for the treatment of HCC. The experimental group had significantly higher scores for awake state and motor activity than the control group.

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CMV pneumonia was diagnosed according to its clinical manifestation, chest X-ray, and etiologic test. This simple and low-cost PCR-RFLP TPMT polymorphism testing approach can be performed in a standard laboratory. Intravenous ibandronate reduces the incidence of skeletal complications in patients with breast cancer and bone metastases. To evaluate treatment patterns using real-world data for patients initiating erectile dysfunction (ED) therapy with Viagra (sildenafil citrate), Levitra (vardenafil), or Cialis (tadalafil). Criteria for the evaluation of alternative environmental monitoring variables: Theory and an application using winter flounder (Pleuronectes americanus) and Dover sole (Microstomus pacificus). Drosophila olfactory aversive conditioning produces two components of intermediate-term memory: anesthesia-sensitive memory (ASM) and anesthesia-resistant memory (ARM).

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EFFECT OF MANGANESE DEFICIENCY UPON THE HISTOLOGY OF LYCOPERSICUM ESCULENTUM. Inhibition of sperm motility by anti-relaxin antiserum has been previously reported. Of interest is the modulatory effect an additional weak oscillating current has on the instantaneous firing rate. A quantitative assay method of Toxoplasma gondii HSP70 mRNA by quantitative competitive-reverse transcriptase-PCR. Notably, UNA monomers can be applied in the design of superior siRNAs, combining potent gene silencing and dramatically reduced off-target effects. Effects of phosphatidylserine in an experimental model of generalized epilepsy. Thus, an exocyclic N-terminal region of only one amino acid residue is sufficient for efficient CCR1 activation. Lack of sufficient accessible community-based health care services for individuals with developmental disabilities has led to disparities in health outcomes and an overreliance on expensive models of care delivered in hospitals and other safety net or state-subsidized providers. To evaluate postradiation regional heart perfusion changes with single photon emission tomography (SPECT) myocardial perfusion imaging in 69 patients treated with tangential photon beams radiation therapy (RT) for left-sided breast cancer. Use of cloth-covered mitral valve prostheses to reduce incidence of embolism.

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Although transesophageal echocardiography is the definitive test for the detection of left atrial (LA) appendage thrombus, transthoracic echocardiography has yet to prove useful for the determination of increased risk for LA appendage thrombus formation. So the genetic polymorphism of ER-alpha gene could affect cancer risk and phenotype. Finally, blood vessel formation within the grafts can be controlled by changing the ratio of endothelial cells. The management of concomitant malignancy and AAA is challenging, especially in patients with a pancreatic tumor. The clinical value of atrial natriuretic peptide in early diagnosis of sepsis. The perturbations caused by radiotherapy and chemotherapy are complex and include reassortment of surviving cells and repopulation. We present the case of a patient who sustained an ipsilateral hip and knee dislocation who underwent closed reduction of the knee in the emergency department but required general anesthesia and the insertion of Schanz pins in the femur to reduce the hip dislocation.

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Variability of environmental exposure to fine particles, black smoke, and trace elements among a Swedish population. This study used the slow developmental sequence and accessibility of the pouch young to investigate the effect of nerve lesions before afferent arrival, or at times when thalamic patterns are obvious but cortical patterns not yet formed. Importantly, intrathecal treatment using GDNF or NTN strongly stimulated axon growth and branching, suggesting that administration of these trophic factors can improve cutaneous innervation deficits caused by diabetes. Development of medicine like celebrex handwriting skill in children with unilateral cerebral palsy (CP). Bactericidal activity of antibiotics as a function of pharmacokinetic constants. Efficacy of monensin sodium for the reduction of fecal shedding of Mycobacterium avium subsp. Current concept of the treatment of interventricular communications with pulmonary hypertension in infants and young children (less than 5-year-old).

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Short-term administration of silybin phosphatidylcholine in patients with advanced HCC resulted in detectable increases in silibinin and its metabolite, silibinin glucuronide. However, the ontogenic profile of the susceptibility does not directly correlate with the levels of NMDAR expression. A stringent degree of significance was obtained by using multiple gene chips. Additional pictures involving stereotype neutral activities also were presented during acquisition and recognition. Subtle spectroscopic differences due to alterations in the spin density distribution at the Cu(II) site can be attributed mainly to changes in the hydrogen-bonding pattern. Microvolt T-wave alternans and the risk of death or sustained ventricular arrhythmias in patients with left ventricular dysfunction. Clinical interventions to address common symptoms associated with treatment should be considered to improve physical and emotional functioning at the end of primary treatment for breast cancer. When the 3 light-curing units were compared at a light-tip distance of 0mm, they showed no significantly different shear bond strengths.

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BIA for the determination of body composition is not influenced by stratum corneum hydration. Effective hair removal in Asians can be difficult, and multiple treatments are usually required for effective treatment. Studies on pancreatic cell physiology rely on the investigation of exocrine and endocrine cells in vitro. The findings provide a better understanding of shoulder exposures associated with medicine cart operations and may be helpful in designing and optimizing the physical environment where medicine carts are used. Osteoclastogenesis in the nonadherent cell population of human bone marrow is inhibited by rhBMP-2 alone or together with rhVEGF.

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Routine screening for Coxiella burnetii infection during pregnancy: a clustered randomised controlled trial during an outbreak, the Netherlands, 2010. Blood lipid effects of antihypertensive therapy: a double-blind comparison of the effects of methyldopa and propranolol. There were reductions in the topographic distribution of axon terminals, in terminal and preterminal branching, and in varicosity density. The death circumstance and toxicity of mice flavoxate tablet uses were observed, ALT and AST in serum were detected. Physiologically based biokinetic (PBBK) model for safrole bioactivation and detoxification in rats.

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Moreover, the activity and content of SIK2 were elevated in white adipose tissues of db/db diabetic mice. The results indicate that the reduction degree of is much lower in SO4(2-) medium than that in Cl(-) medium at pH 7.6. To measure the impact of a rheumatology scientific meeting by examining publication rates of the abstracts in peer-reviewed journals and to investigate factors that influenced publication. These differences underline the importance of taking into account previous experience with pain when recommending strategies to cope with painful procedures. To review the literature with regard to the incidence and prognostic significance of peritoneal seeding during surgery for primary colorectal cancer (CRC), the incidence of intraperitoneal recurrence of CRC, and the current treatment strategies of established PC of colorectal origin, with special focus on cytoreductive surgery and intraperitoneal chemotherapy (IPEC).

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Nineteen studies met the inclusion criteria, in which a total of 815 familial high-risk individuals were compared to 685 controls. Glycosylation is a very common modification of protein and lipid, and most glycosylation reactions occur in the Golgi. Throughout medical training, medical risk management is a subject that has been insufficiently addressed and treated without a global vision. NMDA receptor antagonists ameliorate the stepping deficits produced by unilateral medial forebrain bundle injections of 6-OHDA in rats. The other half of the physicians were told the same patient was a woman. Solvent modification in Merrifield solid-phase peptide synthesis. An alternative approach for the treatment of the degenerative or unstable lumbar spine using glucophage xr drug class retroperitoneal lateral LIF with anterolateral screw-plate or screw-rod fixation is introduced. With recognition and appropriate treatment of affected patients, the potentially fatal consequences of LQTS may be prevented.

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Two criteria, namely, unbiasedness and optimality, are imposed for the filter design. In vivo, in vitro, and in silico studies suggest a conserved immune module that regulates malaria parasite transmission from mammals to mosquitoes. One of the longest running debates in evolutionary biology concerns the kind of genetic variation that is primarily responsible for phenotypic variation in species. White Gold, was measured by following changes in optical density at 520 mmu in buffered 0.25 m sucrose or 0.125 m KCl. Localization of high molecular weight microtubule-associated proteins (MAP1 and MAP2) in a HeLa microtubule-organizing centre. In the present study we examined the long-term effects of CCM signal delivery on the progression of LV dysfunction and remodeling in dogs with chronic HF. We performed a case-control study to investigate the urinary steroid excretions in ovarian cancer patients. Genistein can effectively inhibit the invasive potential of Bel 7402 HCC cells by altering cell cycle, apoptosis and angiogenesis, inhibition of focal adhesion kinase may play a significant role in this process. By using a leucine-incorporation assay, spray of whole plants with 2,4-dichlorophenoxyacetic acid, and wheat coleoptile bioassay, indications were found of an excess of activity and concentration of auxin-like substances in shoots of young and mature mutant plants. Stability during dynamic movements can be estimated from Lyapunov analyses of empirical data.

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We examined the association between S(I), measured using the frequently sampled intravenous glucose tolerance test with minimal model analysis, and incident hypertension (defined as per the Joint National Committee), at the 5-year examination in 840 IRAS participants who were free of hypertension at the baseline examination. Percutaneous transhepatic release of an impacted lithotripter basket and its fractured traction wire adalat cr tablet using a goose-neck snare: a case report. These data indicate that following the institution of PGE and initial medical and ventilatory management, there is an increase in RV annular and septal systolic velocities from the initial to the preoperative period and that these indices as well as RV annular diastolic velocities decline significantly postoperatively. Treatment of the internal mammary nodes in early breast cancer: back to the future. Of this set, 49 QIs were based on ACOVE QIs and 38 QIs were newly added. These effects correlated with altered proportions of hydrogen peroxide and superoxide in root tips and with an inhibition of cell division and elongation. Survival after surgical treatment of early gastric cancer: surgical techniques and long-term survival.

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A checklist consisting of 11 formal quality criteria, 5 quality categories and one global criterion, taken from the literature and from the German Item Management System, was used. The small GTPase Rho1 is known to promote cell wall formation, and we find that Rho1p expressed from a multi-copy plasmid can also rescue sid2-250 at the low restrictive temperature. The purpose of this study was to evaluate the effects of squamous cell carcinoma on oral bacteria. VAD may be effective for providing symptom relief in patients with CVD. Serum intestinal alkaline phosphatase in rats after 800 R whole-body or regional x-irradiation. Therapeutic targets are also found among the axonal channels that set membrane potential and modulate discharge frequency such as voltage sensitive sodium channels and various potassium channels. This could have relevance in terms of enhanced hTERT-dependent tumor cell immunogenicity and suggests new paharmacological approaches interfering with c-Myc dependent pathways. We have maintained hTERT-immortalized progenitor cells derived from a pheochromocytoma (hPheo1) in culture for over 300 population doublings. We identified a positively cis-acting splicing regulatory element (SRE-1) and present two lines of evidence for its functionality.

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