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Nifedipin

Nifedipin is used to treat high blood pressure or angina (chest pain). For high blood pressure: Nifedipin works by relaxing and expanding the blood vessels. This makes the blood flow more easily and lowers blood pressure. Lower blood pressure reduces the strain on your heart. For angina: Nifedipin works by relaxing and expanding the arteries supplying the heart. This allows more blood and oxygen to reach the heart and decreases the strain on it. Your angina attacks will be less severe and less frequent if there is less strain on the heart.

Other names for this medication:
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Also known as: Nifedipine

Description

Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Nifedipin PA 20. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Nifedipin and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

Side effects

The most common side effects associated with Nifedipin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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Clinico-epidemiological profile and high-level aminoglycoside resistance in enterococcal septicemia from a tertiary care hospital in east Delhi. A sigmoidal transcriptional response (STR) is thought to act as a molecular switch to control gene expression. The COI gene trees constructed using the maximum-likelihood and neighbour-joining (NJ) methods supported the monophyly of the booted eagles of the Aquilinae and the sea eagles of the Haliaeetinae but not the kites of the Milvinae. A perfringolysin-deficient mutant, an alpha toxin-deficient mutant and a perfringolysin alpha toxin double mutant were less able to induce necrosis in a calf intestinal loop assay as compared to the wild-type strain. Abnormal neuroimaging in patients with benign epilepsy with centrotemporal spikes. However, most of the current studies focused on the genome-wide screening of CNVs, and the functional impact of such regions needs to be extensively investigated in large number of clinical samples. We describe the study design of an investigator-led UK multi-centre, single arm trial using HIFU to deliver focal therapy for men with localised prostate cancer. A new method for estimation of plasma volume with the use of the distribution space of indium-113m-transferrin. Vision-related functioning outcomes of dexamethasone intravitreal implant in noninfectious intermediate or posterior uveitis. A previously healthy, 54-year-old woman presented with Mycobacterium chelonae soft tissue infection and osteomyelitis of her left lower leg.

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Agglutination of granulocytes from chronic myeloid leukaemia by concanavalin A. Its at present most favourable form of application is the subcutaneous infusion by means of the infusion group. This effect is inhibited by D-galactose and PI3K inhibitors, and is accompanied by an increase in IL-2 receptor expression and by a PI3K-dependent IL-2 gene expression and IL-2 protein synthesis. The biological samples and phenotypic metadata already collected during XE2 will be analysed as an independent study. This report describes an unusual case of a large solitary fibrous tumour (SFT) arising in the retroperitoneum. Calcium alginate tympanic membrane perforation patches offer a significant advantage in the repair of chronic perforations over traditional techniques in the chinchilla perforation model and may offer attractive opportunities in the clinical setting. Here, we introduce zPicture, an interactive Web-based sequence alignment and visualization tool for dynamically generating conservation profiles and identifying evolutionarily conserved regions (ECRs). Young age and EBV seronegativity confer increased risk for ATH in pediatric patients undergoing solid organ transplantation. From opportunism to nascent conservation : The case of the Siona-Secoya.

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Sixty-five patients with drug addictions received operations within the time frame from 2004 to 2009. Unintended adverse consequences of introducing electronic health records in residential aged care homes. The strain distribution estimated by image-based Warping showed excellent agreement with a known forward finite element solution, representing the gold standard, from which the displaced image was created. A retrospective review was performed on all children undergoing LGT placement and PEGs from March 2003 to October 2009. Inhibition of the bronchial response to respiratory heat exchange by increasing doses of terbutaline sulphate.

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Response to: causes of visual disability among Central Africans with diabetes mellitus. Understanding the mechanism by which ADHD risk factors affect the biochemical processes in the human brain and consequentially the behaviour will help to identify novel targets for the development of therapeutics with less adverse results and better efficacy including higher responder rates. Therefore, we hypothesized that cetuximab and irinotecan would be effective in inhibiting the growth and progression of ATC in a murine orthotopic model. Minimally invasive video-assisted thyroidectomy: establishment in a thyroid center. They need healthcare providers to supply them with adequate osteoarthritis disease information. Across the long term, participants in the high-plaque-trajectory group were more likely to experience caries, periodontal disease and subsequent tooth loss than were those in the low- or medium-plaque-trajectory groups, and they experienced all those conditions with greater severity. To compare performance in the perception of brief duration prosodic contrasts by CI participants and a control group of normal hearing participants. The widespread presence in the environment of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), one of the most widely used military explosives, has raised concern owing to its toxicity and recalcitrance to degradation. In particular, N-hydroxy-2-naphthylamine, a proximate carcinogen of 2-naphthylamine could not be detected. Good personal hygiene is one of the most important measures for control of hepatitis infection.

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Effect of age on the attachment rate of the parasitic stages of the lone star tick, Amblyomma americanum (Linnaeus) (Acarina: Ixodidae), in the laboratory. Wild-type male mice preferred females over males, but males lacking central serotonergic neurons lost sexual preference although they were not generally defective in olfaction or in pheromone sensing. Out of more than 5 years of work we illustrate one year with client-data, working-methods and statistical results. The effluent from a small-scale wastewater plant treating toilet and kitchen wastewater contained the target earthy and musty odor compounds below the odor thresholds. Nucleic acid based typing technologies include: PCR, real-time PCR, MLST, MLVA, whole genome sequencing, and microarrays. Identification of human mesothelial cells in culture by electron microscopy and antibodies.

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The combination of long-time, tight-binding molecular dynamics and real-time multiresolution analysis techniques reveals the complexity of small silicon interstitial defects. They are characterized by a distinctive surface ECG and highly responsive to RF ablation at the slow conduction area. Swapping positions between two wild-type polar residues did not affect dimerization, implying a similar contribution from both positions. Abortuses are a valuable source of information relating to congenital defects. Treatment with testosterone induces the excretion of MUPs with the male pattern. Neonatal Sigmoid Colon Perforation: A Rare Occurrence in Low Anorectal Malformation and Review of the Literature. Differences in monolayer growth rates were observed among tumors, but the differences were unrelated to in vivo growth. Leachate, the hazardous liquid that percolated through the refuse layers of a sanitary landfill, if it leaks through the landfill lining system, can become a serious source of groundwater pollution. The distribution of the Anopheles gambiae complex of malaria vectors in Africa is uncertain due to under-sampling of vast regions.

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These findings highlight the need for more epidemiological studies of cervical cancer and pre-cancerous lesions among HIV-positive women in Africa and an improved understanding of incidence and risk factors. Clinico-epidemiologic study in the Chianti area (Tuscany, Italy). Calcium antagonists are associated with reduced mortality after cardiac surgery: a propensity analysis. Comparisons of colorectal cancer mortality between screening participants and the general population are strongly biased unless an incidence-based mortality approach is used. Urinary output of creatinine was similar in diabetic and in nondiabetic groups, and did not vary during exercise. To control the intensity and volume of the workload and also specific features of the regimens used by cosmonauts during SF there were provided monthly 3-days recordings of cosmonaut training sessions with the subsequent downlinking of the obtained information to the ground control center. Dietary intervention has proven effective in lowering serum lipid levels, which are otherwise essential elements in the pathogenesis of cardiovascular disease. This question was addressed by measuring skeletal muscle perfusion using nuclear magnetic resonance imaging combined with arterial spin labeling.

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Superparamagnetic iron oxide nanoparticles (SPION) were used to transfer gene into umbilical cord blood-derived mesenchymal stem cells (UCB-MSCs) in this study. From this cohort, 50 patients (28 male) were included in the study. Posterior predictive distributions indicated that negative-binomial models provided better predictions than Gaussian models, especially when counts were low. Differences in the S3 and S1 binding pockets appeared to account for the species selectivity. Random effects meta-analyses and sensitivity analyses were conducted. The influence of obidoxime, diacetylmonoxime, pralidoxime, and two less hydrophilic derivatives of pralidoxime upon the cholinesterase inhibition and the pressor effect by paraoxon in the rat. A cross-sectional telephone survey was conducted with a convenience sample of patients at 13 Department of Veterans Affairs (VA) Spinal Cord Injury (SCI) Centers between September and November 2000. Retrovirus restriction by TRIM5 proteins requires recognition of only a small fraction of viral capsid subunits. Selective cochlear, SCCs, or saccular destruction had no significant effect on VsEP amplitude, whereas utricular destruction abolished the VsEP completely. One-stage circumferential buccal mucosa graft urethroplasty for bulbous stricture repair.

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Despite the similarities among mammals and invertebrates in insulin-like peptides and their signal cascade, more research is needed to determine whether these signals control aging in the same way in all the species by the same mechanism. In the cued recall test, the first half of correctly perceived sentences was presented, and participants were asked to complete the sentences. Our primary areas of interest include mental health and psychological well-being, obesity, asthma and allergies, health behaviors and health perceptions, comorbidity, and perinatal influences on health outcomes. They are present in nearly all the sequenced genomes of archaea, bacteria and eukaryotes, with the exception of several species with small genomes. No clinical adverse effects or abnormalities on routine blood tests were noted during the study period.

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Furthermore, we could convert an intrabody which does not bind RAS in mammalian cells into a high-affinity reagent capable of inhibiting RAS-mediated NIH 3T3 transformation by exchanging VH and VL complementarity-determining regions onto its consensus scaffold. Solubility properties of a 65-kDa peptide prepared by restricted digestion of myosin with astacin-like squid metalloprotease. The effect of treating inflammatory nasal changes during nocturnal breathing, as well as the role of cephalometry in the prediction of treatment outcome will need further evaluation. The harmonic approximation fails for inversion of the NH2 group in the ground state of aromatic amines as this vibration is characterized by a symmetric double-well potential with relatively small energy barrier. Generally, H2SO4, HNO3, HCl or the combination of ethylenediaminetetraacetate with acetic acid (EDTA-HAc) have been used to preserve arsenite and arsenate species prior to analysis. For this study we adopted a multivariate statistical procedure that allows a global view of the variations induced by different growth conditions, when several variables have to be analyzed simultaneously. A further indication that the behavioural effect of tryptophan was not due to increased brain 5-HT was its prevention by R04-4602 at a dose sufficient to block peripheral but not central L-aromatic amino acid decarboxylase. These results could be used to better define who should price of cleocin 100 mg undergo more intensive rehabilitation aiming to reduce work disability. Fluorescent THF-based fructose analogue exhibits fructose-dependent uptake. Statistical linear models included the effects of age, gender, increased seizure frequency, sleep deprivation, and taper of antiepileptic drugs (AEDs) on mood.

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The types of perivertebral leakage and spinal canal leakage are common among extravertebral cement leakage followed by percutaneous vertebroplasty and kyphoplasty. In particular, the effectiveness of the mechanisms of capillary-gravity waves and the viscous dissipation localized in the vicinity of the perturbation are compared and discussed as functions of H and V. Orthogonal regression is required in order to take into account the error in both axes. In Experiment 2 preschoolers, first, and third graders were asked to judge with the materials directly in front of them, which of the two stars was closer to a site located in one of the subsections. Both of purified nAK and rAK reacted positively with sera from subjects with crustacean allergy in immunoblotting and GICA analysis, indicating AK is a common allergen of mud crab. The effect of environmental temperature on the immune response of a marine teleost (Paralichthys dentatus). It was hypothesized that patients in the first episode of schizophrenia would exhibit dissociable deficits in both WM domains. This study reports the synthesis of regioregular poly(3-hexylthiophene)-b-poly(1H,1H-dihydro perfluorooctyl methacrylate) (P3HT-b-PFOMA) block copolymers by atom transfer radical polymerization of FOMA using P3HT macroinitiators. Spectral characterization of biological aerosol particles using two-wavelength excited laser-induced fluorescence and elastic scattering measurements. Incubation of 100 micromol/L 3,4-DGE resulted in the production of 36 micromol/L 3-DG, 4 micromol/L 5-HMF, and 40 micromol/L unidentified substances.

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The transplanted stem cells expressed angiogenic/neurotrophic factors. pneumoniae serotypes by polymerase chain reaction (PCR) and the Neufeld Quellung reaction, the multilocus sequence types (MLST) by PCR and sequencing, and susceptibility to antimicrobial agents by the VITEK Gram Positive Susceptibility Card. The Stanford Cancer Supportive Care Program was initiated in 1999 to provide support for cancer patients, addressing the need for improved physical and emotional well-being and quality of life. Resonance energy transfer measurements biaxin allergy and penicillin using cobalt bound to the transferase as the acceptor of energy transfer from the dansyl group on the alpha-lactalbumin indicate that the dansyl group is 32 A from the cobalt of the transferase. Intra- and inter-laboratory comparisons of the gel techniques were carried out between the two laboratories involved. Our aim in this study was to determine whether caffeic acid phenethyl ester (CAPE), a non-toxic oxygen free radical scavenger, prevents vasospasm in an experimental rat model of SAH. Reference for sweet taste and the taste of sweeteners in animals. Israel, as a part of the Mediterranean area, is one of the countries with an intermediate risk for NPC. Stepwise discriminant function analyses revealed that variable combinations from the Psychological Screening Inventory and Shipley -Hartford Scale were generally the most effective in identifying disruptive youths, while Jesness Inventory Subscales added little to the classification process.

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In this study, we used a postmenopausal primate model to evaluate interactive effects of dietary soy isoflavones and estrogen on risk markers for breast cancer. Elevated expression of ISG15 in tumor cells interferes with the ubiquitin/26S proteasome pathway. lioresal 25 mg uses These results support the programs focus on screening women aged 50 and older for breast cancer. This paper presents a novel technique to create a computerized fluoroscopy with zero-dose image updates for computer-assisted fluoroscopy-based close reduction and osteosynthesis of diaphyseal fracture of femurs. The aim of this study was to determine whether laparoscopic fundoplication alters gastric myoelectric activity. Furthermore, the formation of malondialdehyde (MDA) increased significantly whereas the activities of superoxide dismutase (SOD), glutathione peroxidase (GSH-PX), catalase (Cat) and glutathione S-transferases (GST) decreased in the cerebral cortex and liver of prenatal intoxicated offspring. Tigecycline represents an exciting new class of glycylcycline antimicrobial agents for the treatment of multi-drug resistant Gram-positive bacteria.

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Specific structured triacylglycerides (STG) containing medium chain fatty acids in sn-1,3 positions and a long chain fatty acid in sn-2 position were prepared from rapeseed oil and capric acid (C10:0). Neuraminidase activity has been found to be characteristic mostly of S. These quadruple mutants are dwarfed and display small curled leaves, aberrant ovules, altered epidermal cells and reduced numbers of lateral roots. The effects of addition of the photosensitizer riboflavin (RF) to semidilute solutions of the systems ethyl(hydroxyethyl)cellulose (EHEC)/water, EHEC/sodium dodecyl sulfate (SDS), and EHEC/cetyltrimethylammonium bromide (CTAB) on the turbidity and the linear viscoelasticity are studied. In all cases, only one pericardial site was dilated at least three times. Glutamine supplementation further enhances exercise-induced plasma IL-6.

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The glycogen staining of the floor plate began to decrease from stage 38, and at the same time neuroglial cells began to migrate into the marginal zone of the floor plate, later than in other regions of the cord. PEA modification of heptose II (HepII) can occur at the 3, 6, or 7 position(s). Unusual superficial stromal corneal deposits in IgG kappa monoclonal gammopathy. Composing a core set of performance indicators for public mental health care: a modified Delphi procedure. An electrochemical reduction released disulfide-conjugated captopril for thiol colorimetry. All of the available evidence suggests that the aglycon sub-site has a highly specific structure which forces the atoms of the aglycon group to occupy well-defined positions. Measurement of macular pigment (MP) can be performed by analysis of autofluorescence (AF) images. Thus, this strategy enables chimeras and/or xenografts to be screened rapidly at the molecular level. Records of cases presenting to GP over a 98-month period (2004-2012) were reviewed. The authors cefaclor paediatric dose surveyed a convenience sample of patients presenting to an urban ED during a four-month period.

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