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Orvas (Ezetimibe)
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Orvas

Orvas is a prescription medicine used to treat the symptoms of high cholesterol and to reduce cholesterol. Orvas may be used alone or with other medications. Orvas belongs to a class of drugs called Lipid-Lowering Agents, 2-Azetidinones. It is not known if Orvas is safe and effective in children younger than 10 years of age.

Other names for this medication:
Atofast, Atolife, Atorvik, Avascare, Bitorva, Etimibe, Ezedoc, Ezentia, Ezerem, Ezetib, Ezetimiba, Ezetimibe, Ezetrol, Ezevas, Ezibloc, Eziwa, Ezzicad, Filet, Imbibe, Lipezet, Liponorm, Mactor, Orvas, Razel, Redustat, Statix, Storvas, Tonact, Visvas, Zeteze, Zetica, Zetimax, Zetivas, Zient, Zivast

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Also known as: Ezetimibe

Description

Orvas (ezetimibe) reduces the level of total cholesterol and LDL (bad) cholesterol in the blood.

Orvas is used to treat high cholesterol in people who cannot control their cholesterol levels by diet and exercise alone.

Orvas works to reduce the amount of cholesterol your body absorbs. You should stay on a cholesterol-lowering diet while taking this medicine.

Orvas is sometimes given together with other cholesterol-lowering medications.

Dosage

Usual Adult Dose of Orvas for Hyperlipidemia:

10 mg orally once a day Uses: -For use as monotherapy or in combination with an HMG-CoA reductase inhibitor (statin) as an adjunct to diet to reduce elevated total cholesterol (total-C), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo B), and non-high-density lipoprotein cholesterol (non-HDL-C) in patients with primary (heterozygous familial and non-familial) hyperlipidemia -For use as combination therapy with fenofibrate as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with mixed hyperlipidemia -As an adjunct to diet to reduce elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia -For use as combination therapy with atorvastatin or simvastatin to reduce elevated total-C and LDL-C levels in patients with homozygous familial hypercholesterolemia, as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable

Usual Adult Dose of Orvas for Homozygous Familial Hypercholesterolemia:

10 mg orally once a day Uses: -For use as monotherapy or in combination with an HMG-CoA reductase inhibitor (statin) as an adjunct to diet to reduce elevated total cholesterol (total-C), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo B), and non-high-density lipoprotein cholesterol (non-HDL-C) in patients with primary (heterozygous familial and non-familial) hyperlipidemia -For use as combination therapy with fenofibrate as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with mixed hyperlipidemia -As an adjunct to diet to reduce elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia -For use as combination therapy with atorvastatin or simvastatin to reduce elevated total-C and LDL-C levels in patients with homozygous familial hypercholesterolemia, as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable

Usual Adult Dose of Orvas for Sitosterolemia:

10 mg orally once a day Uses: -For use as monotherapy or in combination with an HMG-CoA reductase inhibitor (statin) as an adjunct to diet to reduce elevated total cholesterol (total-C), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo B), and non-high-density lipoprotein cholesterol (non-HDL-C) in patients with primary (heterozygous familial and non-familial) hyperlipidemia -For use as combination therapy with fenofibrate as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with mixed hyperlipidemia -As an adjunct to diet to reduce elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia -For use as combination therapy with atorvastatin or simvastatin to reduce elevated total-C and LDL-C levels in patients with homozygous familial hypercholesterolemia, as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable

Usual Pediatric Dose for Hyperlipidemia:

10 years or older: 10 mg orally once a day Uses: -For use as monotherapy or in combination with a statin as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with primary (heterozygous familial and non-familial) hyperlipidemia -For use as combination therapy with a fenofibrate as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with mixed hyperlipidemia -As an adjunct to diet to reduce elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia -For use as combination therapy with atorvastatin or simvastatin for the reduction of elevated total-C and LDL-C in patients with homozygous familial hypercholesterolemia, as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable

Usual Pediatric Dose for Homozygous Familial Hypercholesterolemia:

10 years or older: 10 mg orally once a day Uses: -For use as monotherapy or in combination with a statin as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with primary (heterozygous familial and non-familial) hyperlipidemia -For use as combination therapy with a fenofibrate as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with mixed hyperlipidemia -As an adjunct to diet to reduce elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia -For use as combination therapy with atorvastatin or simvastatin for the reduction of elevated total-C and LDL-C in patients with homozygous familial hypercholesterolemia, as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable

Usual Pediatric Dose for Sitosterolemia:

10 years or older: 10 mg orally once a day Uses: -For use as monotherapy or in combination with a statin as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with primary (heterozygous familial and non-familial) hyperlipidemia -For use as combination therapy with a fenofibrate as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with mixed hyperlipidemia -As an adjunct to diet to reduce elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia -For use as combination therapy with atorvastatin or simvastatin for the reduction of elevated total-C and LDL-C in patients with homozygous familial hypercholesterolemia, as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable

Detailed Orvas dosage information

Overdose

If you overdose Generic Orvas and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Orvas are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Orvas if you are allergic to ezetimibe, or if you have:

moderate to severe liver disease.

Orvas is not approved for use by anyone younger than 10 years old.

You should not use Orvas with a "statin" cholesterol medicine (Zocor, Lipitor, Crestor, and others) if:

you have active liver disease; you are pregnant; or you are breastfeeding a baby.

Statin cholesterol medications can cause the breakdown of muscle tissue, which can lead to kidney failure. This happens more often in women, in older adults, or people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid).

To make sure Orvas is safe for you, tell your doctor if you have:

liver disease; kidney disease; or unexplained muscle pain or weakness.

Tell your doctor if you are pregnant or breastfeeding.

Use effective birth control to prevent pregnancy while you are using Orvas with a statin medicine. Tell your doctor if you plan to become pregnant.

Do not breastfeed if you take Orvas with a statin medicine.

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Cardiovascular effects of vasopressors in isoflurane-anesthetized dogs before and after hemorrhage. The observed switching mechanism, which can be understood in the framework of micromagnetic theory, gives insights into basic magnetization dynamics and their possible application in data storage. The objective of the present review was to compare these two methods. Semi-automated microwave-assisted SPPS: Optimization of protocols and synthesis of difficult sequences. Moreover, alanine substitution at Asp248 or Tyr252 or deletion of Phe246-Tyr252 abolished iC3b ligand recognition as well as the binding of a blocking antibody. Water-mediated conformer optimization in benzo-18-crown-6-ether/water system. The reasons for this results and the possibilities of this findings for the therapy of funcitonal placental insufficiency are discussed. Modulation of MMP-13 activity after rotator cuff repair may offer a novel biological pathway to augment tendon-to-bone healing. We report a patient with unexplained persistent hypereosinophilia associated with a lamisil tablets cost without insurance chronic pruritic rash and an underlying diagnosis of HES (lymphocytic variant). Here we report a case of female Caucasian adult twins with similar presentations of bilateral MMD that were treated with different surgical modalities.

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No asymmetries were disclosed in the rest of time points and structures studied. On the 2nd day after oviposition, round-formed protozoa were found in the ooplasm of the egg. The use of lipopolysaccharide-M-specific mAb in different serological tests instead of polyclonal antisera may be of great practical use for minimizing the risk of the appearance of cross-serological reactions between smooth Brucella strains and Y. The highest picocyanobacteria concentrations occurred in the river, with concentrations an order of magnitude lower at offshore marine stations. Because the gas deposition system used can easily be integrated in a diovan 80 mg generic conventional SEM, the method can be performed in any laboratory equipped with a SEM and an ion milling machine. Three modes for each adenine unit have been included in the Hamiltonian, to describe the main structural changes among the different excited state minima of the adenine stacked dimer, as described at the TD-DFT level. With the use of ultrasound and tomography, a splenic cyst was detected. In depicting the CPK-image on a computer screen, the hidden-point removal is the main task and on such an image, the front-line atoms hide the back-benchers and their whereabouts become completely unknown, in a given view of the picture. A computational investigation of the different intermediates during organoalkoxysilane hydrolysis.

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Eight patients who had their AAA evaluated with MRI are reported. Using flow cytometer and gel image system respectively, we evaluated the TM expression and the t-PA secretion by human umbilical vein endothelial cells (HUVECs) in vitro. However, the molecular mechanisms involved in BV-induced apoptosis are still uncharacterized in human leukemic cells. This anatomical arrangement could make these interneurons considerably more responsive to the excitatory drive from dentate granule cells. At week 22 almost all fibers show a clear membrane immunostaining. In this article some experiences of a dentist practising dentistry on a Caribean Island are described. Such a size limit would influence the construction of models that explain the action of yeast mating factors. Carrier and phonon dynamics in dense arrays of aligned, single-crystal Ge nanowires (NWs) of controlled diameter are investigated by ultrafast optical pump-probe measurements, effective medium calculations, and elasticity analysis.

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Cost cannot be the only consideration in make-or-buy government decisions. Prostate morphogenesis occurs in utero in humans and during the perinatal period in rodents. Here we report on a male infant presenting the typical pattern of Jacobsen syndrome including trigonocephaly, thrombocytopenia, congenital heart defect, urethral stenosis, and partial agenesis of the corpus callosum. High affinity antibody to cobrotoxin prepared from the derivatives of glutaraldehyde-detoxified cobrotoxin. This was due to a cimetidine-induced impairment in microsomal oxidation of diazepam and nordiazepam, which caused a decrease in total metabolic clearance and increased mean steady state plasma concentrations. The immunoperoxidase technique, especially the ABC technique, revealed higher reactivity than the FTA-ABS complement technique and darkfield examination in detecting Treponema pallidum in tissues. A retrospective study was conducted comprising 78 cases of fetal urinary tract obstructions diagnosed by ultrasound. In general, focal or multifocal lesions can be identified by computerized tomography, or diffusion-weighted imaging. Oncogene-induced senescence is a p53-dependent defence mechanism against uncontrolled proliferation.

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