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Piokap (Metformin)

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Piokap is primarily used for the treatment of type 2 diabetes mellitus, particularly in obese.patients. Piokap has been shown to reduce diabetes mortality and complications by thirty percent compared to insulin, glibenclamide and chlorpropamide.

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Also known as: Metformin


Piokap (metformin) is an oral diabetes medicine that helps control blood sugar levels.

Piokap is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

Piokap is sometimes used together with insulin or other medications, but metformin is not for treating type 1 diabetes.


Piokap can be taken in form of pills and extended-release pills which should be taken by mouth. It is better to take Piokap every day at the same time with meal or without it. Usual Piokap dosage is taken 2-3 times a day with meals. Piokap XR (extended-release tablets) is taken once a day with evening meal. Take Piokap and remember that its dosage depends on patient's health state. Piokap can't be used by patients under 10 years. Piokap XR (extended-release tablets) can't be used by patients under 17 years. It can be dangerous to stop Piokap taking suddenly.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can cause severe hypoglycemia or lactic acidosis.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Piokap are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not use Piokap if you are allergic to Piokap components. Try to be careful with Piokap while you are pregnant or have nurseling. Piokap can't be used by patients under 10 years. Piokap XR (extended-release tablets) can't be used by patients under 17 years. Piokap is not taken to treat type 1 diabetes. You can normally take insulin while using Piokap. Do not use Piokap in case of taking probenecid (Benemid); aspirin and other salicylates; sulfa drugs (Bactrim); beta-blockers; monoamine oxidase inhibitor (MAOI); allergies, colds, asthma medicines; thyroid medicine (Synthroid); seizure medicines (Dilantin); phenothiazines (Compazine); diet pills; isoniazid; steroids; hormones including birth control pills. Try to be careful with Piokap in case of using such medication as morphine (MS Contin, Kadian, Oramorph); quinidine (Cardioquin, Quinidex, Quinaglute); vancomycin (Vancocin, Lyphocin); cimetidine (Tagamet) or ranitidine (Zantac); nifedipine (Adalat, Procardia); procainamide (Procan, Pronestyl, Procanbid); trimethoprim (Proloprim, Primsol, Bactrim, Cotrim, Septra); amiloride (Midamor) or triamterene (Dyrenium); digoxin (Lanoxin); furosemide (Lasix). Try to avoid Piokap in case of having lung, kidney, heart or liver disease, high blood pressure, stroke, diabetic ketoacidosis, or kidney failure. Try to avoid Piokap in case you want to undergo an operation (dental or any other), x-ray or CT scan. Try to avoid unhealthy food. Piokap can't be used by patients under 10 years. Piokap XR (extended-release tablets) can't be used by patients under 17 years. If you want to achieve most effective results without any side effects you need to avoid alcohol. It can be dangerous to stop Piokap taking suddenly.

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